Description

3'-Chloro-4'-Methyl[1,1'-Biphenyl]-2-Carboxylic Acid is a high-purity biphenyl carboxylic acid derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its functionalized aromatic structure, which provides a versatile scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging its halogenated biphenyl core.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers due to its rigid, planar biphenyl structure.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.

Basic Information

Product Name	3'-Chloro-4'-Methyl[1,1'-Biphenyl]-2-Carboxylic Acid
CAS No.	71501-51-4
Molecular Formula	C14H11ClO2
Molecular Weight	246.69 g/mol
Synonyms	2-Biphenylcarboxylic acid, 3'-chloro-4'-methyl-; 3'-Chloro-4'-methylbiphenyl-2-carboxylic acid; 2-(3-Chloro-4-methylphenyl)benzoic acid; [1,1'-Biphenyl]-2-carboxylic acid, 3'-chloro-4'-methyl-; 3-Chloro-4-methyl-2-biphenylcarboxylic acid
EINECS	Contact for details

Quality Control

Our 3'-Chloro-4'-Methyl[1,1'-Biphenyl]-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.