Description

Isoxazole, 5-[(Trimethylsilyl)Methyl]- (9Ci) is a specialized organosilicon building block featuring a reactive isoxazole ring system. This compound is valued for its role as a versatile synthon in advanced organic synthesis, particularly in the development of novel heterocyclic compounds and functional materials. It is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the functionalized isoxazole scaffold.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the production of specialty polymers, silicon-based coatings, and advanced resins.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and cycloaddition reactions to create complex heterocyclic systems.
• Ligand Synthesis: Useful for preparing novel ligands for catalysis, given the potential coordinating properties of the isoxazole nitrogen and the silicon moiety.

Basic Information

Product Name	Isoxazole, 5-[(Trimethylsilyl)Methyl]- (9Ci)
CAS No.	71482-87-6
Molecular Formula	C7H13NOSi
Molecular Weight	155.27 g/mol
Synonyms	5-[(Trimethylsilyl)methyl]isoxazole; 5-(Trimethylsilylmethyl)isoxazole; 5-[(Trimethylsilyl)methyl]-1,2-oxazole; 5-(Trimethylsilylmethyl)-1,2-oxazole; (5-Isoxazolylmethyl)trimethylsilane; Trimethyl(5-isoxazolylmethyl)silane
EINECS	Contact for details

Quality Control

Our Isoxazole, 5-[(Trimethylsilyl)Methyl]- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR, GC, and HPLC, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality system is designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.