Description

4'-Hydroxymethylbenzo-18-Crown-6 is a functionalized crown ether derivative, specifically a benzo-18-crown-6 ether with a hydroxymethyl group at the 4' position. This compound is valued for its selective ion-binding capabilities, particularly for potassium and ammonium cations, making it a crucial component in phase-transfer catalysis, chemical sensors, and separation science. It is primarily utilized by researchers and manufacturers in the pharmaceutical, analytical chemistry, and materials science industries for developing advanced extraction systems, membrane transport agents, and supramolecular assemblies.

Application

• Phase-Transfer Catalyst (PTC): Facilitates reactions between reagents in immiscible phases, enhancing reaction rates and yields in organic synthesis.
• Ion-Selective Electrodes & Sensors: Serves as an ionophore in the membrane of potentiometric sensors for detecting potassium (K⁺) or ammonium (NH₄⁺) ions.
• Liquid-Liquid Extraction: Used for the selective separation and pre-concentration of specific metal ions from complex mixtures in analytical and industrial processes.
• Membrane Transport Studies: Acts as a model carrier in artificial membranes to study and mimic biological ion transport mechanisms.
• Supramolecular Chemistry: A building block for constructing host-guest complexes, molecular machines, and functional materials.
• Pharmaceutical Intermediates: Can be employed in the synthesis of more complex crown ether derivatives with targeted biological activity.

Basic Information

Product Name	4'-Hydroxymethylbenzo-18-Crown-6
CAS No.	71015-62-8
Molecular Formula	C₁₉H₃₀O₇
Molecular Weight	370.44 g/mol
Synonyms	4-(Hydroxymethyl)benzo-18-crown-6; Benzo-18-crown-6, 4'-(hydroxymethyl)-; 4'-Hydroxymethylbenzo-18-crown-6 Ether; 4-(Hydroxymethyl)-1,4,7,10,13,16-hexaoxacyclooctadeca-2,5,8,11,14,17-hexaene; 4-(Hydroxymethyl)benzo-18-crown-6 ether; 4'-HM-B18C6; HM-B18C6
EINECS	Contact for details

Quality Control

Our 4'-Hydroxymethylbenzo-18-Crown-6 is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial applications. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.