Description

Isoxanthohumol is a prenylated flavonoid primarily derived from hops (*Humulus lupulus*). This compound is of significant commercial interest due to its potent biological activities, particularly its role as a key metabolic precursor to the more potent phytoestrogen, 8-prenylnaringenin. It is sought after by manufacturers in the nutraceutical, pharmaceutical, and cosmetic industries for inclusion in dietary supplements, functional food ingredients, and advanced skincare formulations targeting antioxidant and hormonal balance benefits.

Application

• Nutraceutical & Dietary Supplements: A key ingredient in formulations designed to support menopausal health, bone density, and overall antioxidant defense.
• Functional Food & Beverage: Used as a bioactive component in health-focused foods and drinks, leveraging its origin from hops.
• Pharmaceutical Research & Development: Serves as a critical reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel therapeutics.
• Cosmetic & Skincare Products: Incorporated into anti-aging and protective skincare formulations for its antioxidant and potential phytoestrogenic properties.
• Analytical & Quality Control: Used as a high-purity certified reference material (CRM) for HPLC and LC-MS analysis in laboratory and quality assurance settings.
• Sports Nutrition: Included in specialized supplements aimed at recovery and metabolic support.

Basic Information

Product Name	Isoxanthohumol
CAS No.	70872-29-6
Molecular Formula	C21H22O5
Molecular Weight	354.40 g/mol
Synonyms	Isoxanthohumol; 5-Hydroxy-8-prenylnaringenin; 2-(2,4-Dihydroxyphenyl)-5-hydroxy-8-(3-methylbut-2-en-1-yl)-7-(3-methylbut-2-en-1-yl)chroman-4-one; 3'-(3-Methylbut-2-en-1-yl)-2',4,4'-trihydroxychalcone; Isoxanthogalenol; Prenylnaringenin derivative
EINECS	Contact for details

Quality Control

Our Isoxanthohumol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, UV), to ensure it meets stringent specifications for nutraceutical and research applications. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥95.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals (as Pb)	≤20 ppm
Solvent Residues	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.