Description

(S)-2-(Toluene-4-Sulfonyloxy)-Propionic Acid is a high-purity chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key precursor for introducing the (S)-2-propionic acid moiety into more complex molecules, enabling the creation of enantiomerically pure compounds. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of enantiomerically pure Active Pharmaceutical Ingredients (APIs), especially non-steroidal anti-inflammatory drugs (NSAIDs) and other carboxylic acid-based therapeutics.
• Agrochemical Synthesis: Used in the research and production of chiral herbicides, fungicides, and plant growth regulators where specific stereochemistry is required for biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Manufacturing: Employed in the custom synthesis of complex, high-value specialty chemicals for research and industrial applications.
• Academic and R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research within university and corporate laboratories.

Basic Information

Product Name	(S)-2-(Toluene-4-Sulfonyloxy)-Propionic Acid
CAS No.	70836-98-5
Molecular Formula	C10H12O5S
Molecular Weight	244.26 g/mol
Synonyms	(S)-2-[(4-Methylphenyl)sulfonyloxy]propanoic acid; (S)-2-(p-Toluenesulfonyloxy)propionic acid; D-(-)-2-(p-Toluenesulfonyloxy)propionic acid; (S)-O-Tosyl lactic acid; (S)-Lactic acid tosylate; (S)-2-Hydroxypropionic acid 4-methylbenzenesulfonate; Tosyl-(S)-lactic acid; (S)-Tosyl lactate
EINECS	Contact for details

Quality Control

Our (S)-2-(Toluene-4-Sulfonyloxy)-Propionic Acid is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including chiral HPLC, to verify enantiomeric excess and identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.