Description

1,1'-Biphenyl, 2-Bromo-4-(1,1-Dimethylethyl)- is a high-purity, synthetically valuable brominated biphenyl derivative. This compound serves as a critical advanced intermediate in the synthesis of complex organic molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by R&D chemists and process development scientists for constructing molecules that require a sterically hindered, halogenated biphenyl core structure.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders or as kinase inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators where the biphenyl scaffold provides biological activity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized phosphine or N-heterocyclic carbene (NHC) ligands used in transition metal catalysis.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers where its structure can influence electronic properties and molecular ordering.
• Chemical Research & Development: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Negishi) and for introducing steric bulk in molecular design during early-stage discovery.

Basic Information

Product Name	1,1'-Biphenyl, 2-Bromo-4-(1,1-Dimethylethyl)-
CAS No.	70729-01-0
Molecular Formula	C16H17Br
Molecular Weight	289.21 g/mol
Synonyms	2-Bromo-4-tert-butylbiphenyl; 4-tert-Butyl-2-bromobiphenyl; 2-Bromo-4-(1,1-dimethylethyl)-1,1'-biphenyl; 2-Bromo-4-tert-butyl-1,1'-biphenyl; 2-Bromo-4-(tert-butyl)biphenyl; 1,1'-Biphenyl, 2-bromo-4-(1,1-dimethylethyl)-; 2-Bromo-4-tert-butylbiphenyl
EINECS	Contact for details

Quality Control

Our 1,1'-Biphenyl, 2-Bromo-4-(1,1-Dimethylethyl)- is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profile data is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.