Description

1,4,7,10,13,16-Hexaoxacyclooctadecane-2-Methanol is a functionalized crown ether derivative, specifically a hydroxymethyl-substituted 18-crown-6 ether. This compound is valued for its ability to selectively bind cations, particularly potassium ions, making it a crucial tool in chemical synthesis, separation science, and sensor technology. It is primarily utilized by researchers and manufacturers in the pharmaceutical, analytical chemistry, and materials science industries for applications requiring precise molecular recognition or phase-transfer catalysis.

Application

• Phase-Transfer Catalyst (PTC): Facilitates reactions between reagents in immiscible phases, enhancing reaction rates and yields in organic synthesis.
• Ionophore for Sensors: Serves as a key selective component in ion-selective electrodes (ISEs) and optical sensors for potassium ion detection.
• Metal Ion Extraction & Separation: Used in liquid-liquid extraction processes to selectively separate and purify specific metal ions from complex mixtures.
• Pharmaceutical Intermediate: Acts as a building block or complexing agent in the synthesis of more complex molecules for drug development.
• Polymer Modification: The hydroxymethyl group allows for covalent attachment to polymers, creating crown ether-functionalized materials for specialized membranes or resins.
• Analytical Chemistry Reagent: Employed in chromatography and capillary electrophoresis as a mobile phase additive to improve separation of ionic species.

Basic Information

Product Name	1,4,7,10,13,16-Hexaoxacyclooctadecane-2-Methanol
CAS No.	70069-04-4
Molecular Formula	C13H26O7
Molecular Weight	294.34 g/mol
Synonyms	18-Crown-6-2-methanol; 2-(Hydroxymethyl)-18-crown-6; 2-(Hydroxymethyl)-1,4,7,10,13,16-hexaoxacyclooctadecane; Hydroxymethyl-18-crown-6; Monohydroxymethylated 18-crown-6; 18-Crown-6 ether, 2-(hydroxymethyl)-; Potassium ionophore I; Aza-18-crown-6 ether derivative (common class reference)
EINECS	Contact for details

Quality Control

Our 1,4,7,10,13,16-Hexaoxacyclooctadecane-2-Methanol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing purity (typically by HPLC or titration), water content, and other critical parameters are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider the use of a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.