Description

4-Aminobenzamidine Hydrochloride is a high-purity, small molecule inhibitor primarily used in biochemical and pharmaceutical research. Its core value lies in its potent and selective inhibition of serine proteases like trypsin, thrombin, and plasmin, making it a critical tool for studying enzymatic pathways. This compound is essential for researchers and manufacturers in the fields of proteomics, drug discovery, and diagnostic assay development, where precise enzyme control is required.

Application

• Biochemical Research: A key inhibitor for studying the kinetics, structure, and function of serine proteases in vitro.
• Pharmaceutical Development: Used as a reference standard and pharmacophore in the design of novel anticoagulant and anti-inflammatory drug candidates.
• Diagnostic Reagents: Incorporated into diagnostic kits and assays to control proteolytic activity and ensure test accuracy and stability.
• Cell Culture & Proteomics: Employed to prevent unwanted protein degradation in cell lysates and protein samples during preparation and analysis.
• Enzyme Purification: Utilized in affinity chromatography for the purification of specific serine proteases from complex mixtures.

Basic Information

Product Name	4-Aminobenzamidine Hydrochloride
CAS No.	7761-72-0
Molecular Formula	C7H10N4·HCl
Molecular Weight	186.64 g/mol
Synonyms	p-Aminobenzamidine Hydrochloride; Benzamidine, 4-amino-, hydrochloride; 4-Amidinobenzeneamine Hydrochloride; 4-Amino-benzenecarboximidamide Hydrochloride; (4-Aminophenyl)methanimidamide Hydrochloride; Trypsin Inhibitor (small molecule); APBA·HCl
EINECS	231-826-5

Quality Control

Our 4-Aminobenzamidine Hydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.