Description

trans-4-Isopropylcyclohexanecarboxylic acid is a versatile, high-purity organic acid derivative of cyclohexanecarboxylic acid, featuring a trans-configured isopropyl group at the 4-position. This specific stereochemistry and functional group combination make it a valuable chiral building block and intermediate in advanced organic synthesis. It is essential for research and development chemists and process engineers in the pharmaceutical and fine chemical industries. The compound's structure is particularly useful for constructing complex molecules where stereochemical control and lipophilicity are critical parameters.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting central nervous system and metabolic disorders.
• Liquid Crystal Material Synthesis: Used in the production of advanced liquid crystal compounds for display technologies, where the cyclohexane ring and isopropyl group contribute to desired mesomorphic properties.
• Perfumery and Flavor Chemistry: Acts as a starting material for the synthesis of musky or woody fragrance compounds and flavoring agents due to its stable, functionalized cyclohexane backbone.
• Agrochemical Intermediate: Employed in the research and development of novel herbicides and fungicides, where its structure can be incorporated to modulate biological activity and environmental stability.
• Organic Synthesis Building Block: A valuable reagent for stereoselective synthesis, including asymmetric hydrogenation and cross-coupling reactions, to create complex, optically active molecules.
• Polymer Modification: Used to introduce sterically hindered, hydrophobic side chains into polymers to alter physical properties like glass transition temperature and solubility.

Basic Information

Item	Detail
Product Name	trans-4-Isopropylcyclohexanecarboxylic acid
CAS No.	7707-05-6
Molecular Formula	C10H18O2
Molecular Weight	170.25 g/mol
Synonyms	(1r,4r)-4-(1-Methylethyl)cyclohexanecarboxylic acid; (trans)-4-Isopropylcyclohexanecarboxylic acid; 4-Isopropylcyclohexanecarboxylic acid, trans-; p-Isopropylcyclohexanecarboxylic acid; trans-4-(1-Methylethyl)cyclohexanecarboxylic acid; 4-(Propan-2-yl)cyclohexane-1-carboxylic acid; NSC 3341
EINECS	Contact for details

Quality Control

Our trans-4-Isopropylcyclohexanecarboxylic acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee (trans isomer)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.