Description

Natamycin is a potent, naturally occurring polyene macrolide antifungal agent produced by fermentation of *Streptomyces natalensis*. This compound is highly valued for its selective activity against yeasts and molds, making it a critical preservative and antifungal agent in various industries. It is essential for manufacturers in the food and beverage, pharmaceutical, and personal care sectors seeking effective, natural solutions to prevent spoilage and contamination.

Application

• Food & Beverage Preservation: Widely used as a natural preservative (E235) on the surface of cheese, sausages, and baked goods to inhibit mold and yeast growth.
• Pharmaceutical Formulations: Employed as an active pharmaceutical ingredient (API) in topical antifungal preparations for the treatment of ocular, dermal, and mucosal infections.
• Agricultural Applications: Used in post-harvest treatments to protect fruits and vegetables from fungal decay during storage and transport.
• Dairy Industry: Applied in the production of yogurt and other cultured dairy products to prevent surface mold contamination.
• Animal Feed Additive: Incorporated into feed to prevent mycotoxin formation and fungal spoilage, ensuring feed safety and quality.
• Personal Care Products: Utilized in creams, lotions, and other cosmetic formulations as a preservative against cosmetic-spoiling microorganisms.

Basic Information

Product Name	Natamycin
CAS No.	7681-93-8
Molecular Formula	C33H47NO13
Molecular Weight	665.73 g/mol
Synonyms	Pimaricin; Natacyn; Myprozine; Antibiotic A-5283; E 235; Tennecetin; CL 12625; Delvocid
EINECS	231-683-5

Quality Control

Our Natamycin is produced and tested to meet stringent quality standards, including Food Chemicals Codex (FCC) and pharmaceutical-grade specifications where applicable. Every batch undergoes comprehensive analysis for potency, purity, and microbiological safety. Certificates of Analysis (COA) detailing assay, impurities, and specific tests are available upon request to ensure full traceability and compliance with your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and potency.

Specification

Item	Specification
Appearance	White to creamy-white powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 95.0%
pH (1% Suspension)	5.0 - 7.5
Loss on Drying	≤ 8.0%
Specific Rotation	+250° to +295°
Heavy Metals	≤ 20 ppm
Total Aerobic Microbial Count	≤ 100 cfu/g

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.