Description

n-2-Nitrophenylsulfenyl-L-Valine Dicyclohexylammonium Salt is a high-purity, protected amino acid derivative primarily used as a critical building block in solid-phase peptide synthesis (SPPS). This compound is valued for its role in introducing the valine residue while providing orthogonal protection for the sulfhydryl group, enabling complex peptide chain assembly. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors developing therapeutic peptides, peptide hormones, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of L-valine into peptide sequences.
• Pharmaceutical Research: Used in the development and production of novel therapeutic peptides and peptide-based drugs.
• Bioconjugation: Serves as a reagent for site-specific modification of proteins and other biomolecules via its protected thiol group.
• Combinatorial Chemistry: Employed in libraries for drug discovery and structure-activity relationship (SAR) studies.
• Biochemical Reagent: Used in enzymatic studies and as a substrate or inhibitor in biochemical assays.
• Academic & Industrial R&D: Fundamental research tool in organic chemistry, medicinal chemistry, and molecular biology laboratories.

Basic Information

Product Name	n-2-Nitrophenylsulfenyl-L-Valine Dicyclohexylammonium Salt
CAS No.	7675-57-2
Molecular Formula	C23H37N3O4S
Molecular Weight	451.63 g/mol
Synonyms	NSC 334365; Nps-Val-OH·DCHA; L-Valine, N-[(2-nitrophenyl)thio]-, compd. with dicyclohexylamine (1:1); 2-Nitrophenylsulfenyl-L-valine dicyclohexylammonium salt; Nps-L-Valine DCHA salt; (S)-2-((2-Nitrophenyl)thio)-3-methylbutanoic acid dicyclohexylammonium salt; DCHA salt of Nps-Val-OH
EINECS	Contact for details

Quality Control

Our n-2-Nitrophenylsulfenyl-L-Valine Dicyclohexylammonium Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and optical rotation analysis, to ensure high chemical purity and chiral integrity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee batch-to-batch consistency and support your research and cGMP-compliant manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]D20	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.