Description

Cyclohexylzinc Bromide is a highly reactive organozinc reagent, specifically an organozinc halide, widely used in organic synthesis. Its core value proposition lies in its ability to act as a nucleophilic source of the cyclohexyl group, enabling efficient carbon-carbon bond formation under mild conditions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable synthetic building blocks for complex molecule construction.

Application

Cyclohexylzinc Bromide (CAS 7565-57-3) is a versatile reagent for introducing the cyclohexyl moiety into target molecules. Key applications include:

• Negishi Cross-Coupling Reactions: Palladium-catalyzed coupling with aryl or vinyl halides to form substituted cyclohexylarenes or alkenes.
• Nucleophilic Addition to Carbonyls: Addition to aldehydes and ketones for the synthesis of secondary and tertiary cyclohexyl carbinols.
• Pharmaceutical Intermediate Synthesis: Construction of bioactive molecules and active pharmaceutical ingredients (APIs) containing the cyclohexyl ring system.
• Agrochemical Synthesis: Manufacturing of herbicides, fungicides, and other crop protection agents.
• Ligand and Catalyst Development: Preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Material Science Research: Synthesis of monomers and polymers with cyclohexyl side chains for advanced polymeric materials.

Basic Information

Product Name	Cyclohexylzinc Bromide
CAS No.	7565-57-3
Molecular Formula	C6H11BrZn
Molecular Weight	204.45 g/mol
Synonyms	Bromocyclohexylzinc; Zinc, bromocyclohexyl-; Cyclohexylzinc bromide solution; Cyclohexylzinc bromide, 0.5M in THF; Cyclohexylzinc bromide, 0.5M in diethyl ether; Bromo(cyclohexyl)zinc; (Cyclohexyl)zinc bromide
EINECS	Contact for details

Quality Control

Our Cyclohexylzinc Bromide is produced and handled under stringent quality protocols. Each batch undergoes rigorous analytical testing to ensure consistency, purity, and performance in critical synthetic applications. A comprehensive Certificate of Analysis (COA) detailing assay, concentration, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. This material is easily oxidized and must be stored under an inert atmosphere (argon or nitrogen). Recommended storage temperature is 2-8°C for solutions. Keep away from heat, sparks, open flames, and strong oxidizing agents. Use only in a well-ventilated area or fume hood.

Specification

Item	Specification
Appearance (Solution)	Colorless to pale yellow solution
Concentration (Typical)	0.5 M in THF or Diethyl Ether
Assay (Titration)	≥ 95%
Identification (IR / NMR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.