Description

(2-Chloromethyl)-5-Hydroxy-4H-Pyran-4-One CAS NO 7559-81-1 is a versatile heterocyclic building block and key synthetic intermediate. This compound is valued for its reactive chloromethyl and hydroxyl functional groups, which enable its use in the synthesis of more complex molecules. It is primarily required by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with pyran or pyridine-based structures.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and other crop protection agents.
• Fine Chemical Building Block: Serves as a versatile starting material for synthesizing complex organic molecules, dyes, and functional materials in research and development.
• Ligand and Catalyst Preparation: Employed in the preparation of specialized ligands for metal catalysis and coordination chemistry.
• Material Science Research: Investigated as a monomer or cross-linking agent in the development of novel polymers and advanced materials.

Basic Information

Product Name	(2-Chloromethyl)-5-Hydroxy-4H-Pyran-4-One
CAS No.	7559-81-1
Molecular Formula	C6H5ClO3
Molecular Weight	160.55 g/mol
Synonyms	5-Hydroxy-2-(chloromethyl)-4H-pyran-4-one; 2-Chloromethyl-5-hydroxy-4-pyrone; 5-Hydroxy-2-chloromethyl-4-pyrone; Kojic acid chloromethyl ether; 2-(Chloromethyl)-5-hydroxy-4H-pyran-4-one; 2-Chloromethyl-5-hydroxy-γ-pyrone; 5-Hydroxy-2-(chloromethyl)-4-pyrone
EINECS	231-447-5

Quality Control

Our (2-Chloromethyl)-5-Hydroxy-4H-Pyran-4-One is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay, impurity profile, and physical characteristics. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.