Description

1-Oxo-3,4,4A,7,8,8A-Hexahydroisochromene-5-Carboxylic Acid is a specialized organic compound belonging to the class of hexahydroisochromene derivatives, valued for its unique bicyclic lactone-carboxylic acid structure. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in synthetic organic chemistry. It is primarily required by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used as a precursor in the development of new pesticides and herbicides, leveraging its complex bicyclic framework.
• Fine Chemical Production: Serves as a sophisticated building block for synthesizing flavors, fragrances, and other high-value specialty chemicals.
• Academic & Industrial R&D: Employed in methodological studies and process chemistry for constructing complex heterocyclic systems.
• Material Science Research: Investigated as a monomer or precursor for novel polymers with specific thermal or optical properties.

Basic Information

Product Name	1-Oxo-3,4,4A,7,8,8A-Hexahydroisochromene-5-Carboxylic Acid
CAS No.	7252-26-8
Molecular Formula	C10H12O4
Molecular Weight	196.20 g/mol
Synonyms	5-Carboxy-1-oxo-3,4,4a,7,8,8a-hexahydroisochromene; 1-Oxo-3,4,4a,7,8,8a-hexahydro-1H-isochromene-5-carboxylic acid; Hexahydroisochromene-5-carboxylic acid derivative; 3,4,4a,7,8,8a-Hexahydro-1-oxoisochromene-5-carboxylic acid; 5-Carboxy-3,4,4a,7,8,8a-hexahydroisochromen-1-one; Bicyclic lactone-carboxylic acid intermediate
EINECS	Contact for details

Quality Control

Our 1-Oxo-3,4,4A,7,8,8A-Hexahydroisochromene-5-Carboxylic Acid is produced under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment ensures the material meets the exacting standards required for GMP-grade intermediates and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.