Description

2,3,4,5,6-Pentafluorophenyl 5-(Dimethylamino)-1-Naphthalenesulfonate is a specialized fluorinated sulfonate ester derivative, serving as a critical building block and reagent in advanced organic synthesis. Its core value lies in its unique structure, which combines a highly electron-deficient pentafluorophenyl group with a fluorescent dimethylaminonaphthalene (dansyl) moiety, making it a powerful tool for labeling and derivatization. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require high-purity, functionalized intermediates for developing novel active ingredients and fluorescent probes.

Application

• Fluorescent Labeling Reagent: Used as a derivatizing agent for amines, alcohols, and thiols in HPLC and LC-MS analysis to enhance detection sensitivity due to its strong fluorescence.
• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of complex drug candidates, particularly those requiring fluorinated aromatic systems for improved metabolic stability and bioavailability.
• Bioconjugation Chemistry: Employed for tagging proteins, peptides, and other biomolecules to study biological interactions and pathways via fluorescence spectroscopy or microscopy.
• Polymer and Material Science: Acts as a functional monomer or cross-linking agent in the development of specialty polymers with unique optical or surface properties.
• Agrochemical Research: Utilized in the design and synthesis of new generation pesticides and herbicides that incorporate fluorinated components for enhanced activity.
• Chemical Biology Probes: Integral for creating activity-based probes and sensors to detect enzymatic activity or specific ions in complex biological systems.

Basic Information

Item	Details
Product Name	2,3,4,5,6-Pentafluorophenyl 5-(Dimethylamino)-1-Naphthalenesulfonate
CAS No.	7243-06-3
Molecular Formula	C18H12F5NO3S
Molecular Weight	417.35 g/mol
Synonyms	5-(Dimethylamino)naphthalene-1-sulfonic acid 2,3,4,5,6-pentafluorophenyl ester; Dansyl pentafluorophenyl ester; Dns-OSu analogue (PFP ester); PFP-Dansylate; 1-Dimethylaminonaphthalene-5-sulfonyl pentafluorophenyl ester; Pentafluorophenyl dansylsulfonate; Fluorogenic labeling reagent PFP ester
EINECS	Contact for details

Quality Control

Every batch of 2,3,4,5,6-Pentafluorophenyl 5-(Dimethylamino)-1-Naphthalenesulfonate is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.