Description

4-Hydroxybut-2-Ynoic Acid is a versatile bifunctional organic compound featuring both a terminal alkyne and a carboxylic acid group, making it a valuable building block in synthetic chemistry. This unique structure enables its use as a key intermediate for the synthesis of complex molecules, including pharmaceuticals, agrochemicals, and advanced materials. It is particularly sought after by research institutions and industrial manufacturers in the fine chemical, pharmaceutical, and material science sectors for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of various active pharmaceutical ingredients (APIs), especially those requiring alkyne functionality for click chemistry or further derivatization.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and plant growth regulators where its reactive groups allow for the construction of specific bioactive scaffolds.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for creating specialty polymers, dendrimers, and functional coatings with tailored properties.
• Bioconjugation & Probe Development: The terminal alkyne group is ideal for Huisgen cycloaddition (click chemistry) reactions, facilitating the labeling of biomolecules for diagnostics and research.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to construct heterocycles, complex natural product analogs, and other fine chemicals.

Basic Information

Product Name	4-Hydroxybut-2-Ynoic Acid
CAS No.	7218-52-2
Molecular Formula	C4H4O3
Molecular Weight	100.07 g/mol
Synonyms	2-Butynoic acid, 4-hydroxy-; 4-Hydroxy-2-butynoic acid; 3-Carboxyprop-1-yn-1-ol; 4-Hydroxybut-2-ynoic acid; 2-Butynoic acid, 4-hydroxy- (9CI); 4-Hydroxy-2-butynoate; 4-Hydroxybutynoic acid; 4-Hydroxybut-2-ynoate
EINECS	Contact for details

Quality Control

Our 4-Hydroxybut-2-Ynoic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request, providing full traceability and quality assurance for your projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials such as strong oxidizing agents, bases, and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.