Description

2-(Bromomethyl)Benzoic Acid is a versatile aromatic carboxylic acid derivative, serving as a key bifunctional building block in advanced organic synthesis. Its molecular structure, featuring both a reactive benzylic bromide and a carboxylic acid group, makes it invaluable for constructing complex molecules through sequential functionalization. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications ranging from drug intermediate synthesis to materials science.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with benzyl-linked pharmacophores.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that require aromatic acid frameworks.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands for metal catalysis and organocatalysts.
• Polymer Modification: Employed to introduce carboxylic acid functionality into polymers or as a cross-linking agent for specialty resins.
• Peptide Mimetics and Bioconjugation: The carboxylic acid group enables amide bond formation, while the bromomethyl group allows for alkylation, useful in creating peptide analogs and bioconjugation linkers.
• Material Science Research: Applied in the development of organic semiconductors, metal-organic frameworks (MOFs), and other functional materials.

Basic Information

Product Name	2-(Bromomethyl)Benzoic Acid
CAS No.	7115-89-1
Molecular Formula	C8H7BrO2
Molecular Weight	215.05 g/mol
Synonyms	2-(Bromomethyl)benzoic acid; o-(Bromomethyl)benzoic acid; 2-Bromomethylbenzoic acid; Benzoic acid, 2-(bromomethyl)-; (2-Bromomethyl)benzoic acid; α-Bromo-o-toluic acid; NSC 403107; 2-Carboxybenzyl bromide
EINECS	230-432-8

Quality Control

Our 2-(Bromomethyl)Benzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets exacting standards for research and industrial use. A detailed Certificate of Analysis (COA) documenting purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under anhydrous conditions to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.