Description

Trimethyl(4-Phenylbutyl)Silane is a specialized organosilicon compound featuring a phenylbutyl chain linked to a trimethylsilyl group. This unique structure makes it a valuable intermediate and protecting group reagent in advanced organic synthesis, particularly for the pharmaceutical and agrochemical industries. It is primarily sought after by R&D chemists and process development scientists for constructing complex molecules where selective protection and controlled reactivity are required.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring silicon-containing moieties or protected functional groups.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides, where the silane group can modify biological activity and stability.
• Advanced Material Precursor: Serves as a monomer or modifying agent in the development of specialty silicones, siloxane polymers, and surface-modifying coatings.
• Organic Synthesis Reagent: Functions as a versatile reagent for introducing the trimethylsilyl group, acting as a protecting group for alcohols or as a precursor to other organosilicon compounds.
• Liquid Crystal & OLED Material Research: Employed in the synthesis of organic semiconductors and liquid crystal molecules for electronic displays.
• Cross-Coupling Reactions: Can be utilized in palladium-catalyzed cross-coupling reactions, such as the Hiyama coupling, due to the presence of the silicon-carbon bond.

Basic Information

Product Name	Trimethyl(4-Phenylbutyl)Silane
CAS No.	777-82-2
Molecular Formula	C₁₃H₂₂Si
Molecular Weight	206.40 g/mol
Synonyms	(4-Phenylbutyl)trimethylsilane; Trimethyl(4-phenylbutyl)silane; 4-Phenylbutyltrimethylsilane; Silane, trimethyl(4-phenylbutyl)-; 1-Trimethylsilyl-4-phenylbutane; (4-Phenylbutyl)trimethylsilicon; NSC 163046
EINECS	212-307-3

Quality Control

Our Trimethyl(4-Phenylbutyl)Silane is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical parameters. Our quality commitment ensures the material meets the stringent requirements for research and commercial-scale synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.485 - 1.495
Density (20°C)	0.87 - 0.89 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.