Description

Fluorosulfuric Acid 4-Methoxyphenyl Ester is a specialized organosulfur compound used as a key intermediate in advanced organic synthesis. This high-purity reagent is valued for its role in introducing the fluorosulfonate group, a versatile leaving group and functional handle in complex molecule construction. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty materials industries for building novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring aryl fluorosulfonate motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the 4-methoxyphenyl fluorosulfonate moiety is integral to biological activity.
• Cross-Coupling Reactions: Serves as an effective electrophile in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for biaryl and heteroaryl bond formation.
• Polymer & Material Science: Employed as a monomer or functionalization agent in the production of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Research & Development: A valuable reagent in academic and industrial labs for methodological development and exploring new reaction pathways in organofluorine chemistry.

Basic Information

Product Name	Fluorosulfuric Acid 4-Methoxyphenyl Ester
CAS No.	775-27-9
Molecular Formula	C7H7FO4S
Molecular Weight	206.19 g/mol
Synonyms	4-Methoxyphenyl fluorosulfonate; p-Methoxyphenyl fluorosulfonate; Fluorosulfonic acid 4-methoxyphenyl ester; 4-Methoxyphenyl fluoro sulfate; 1-Methoxy-4-fluorosulfonyloxybenzene; (4-Methoxyphenoxy)sulfuryl fluoride; FSO2OC6H4OCH3 (p-)
EINECS	Contact for details

Quality Control

Every batch of Fluorosulfuric Acid 4-Methoxyphenyl Ester is manufactured and tested under strict quality management protocols to ensure consistency and reliability for sensitive synthetic applications. Our standard grade typically meets a purity specification of ≥97% (by HPLC/NMR), with rigorous control of key impurities. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.