Description

4-Methoxybicyclo[2.2.2]octane-1-carboxylic acid is a specialized bicyclic carboxylic acid derivative featuring a methoxy substituent, offering a unique sterically hindered and functionalized molecular scaffold. This compound is valued for its role as a sophisticated building block in advanced organic synthesis and pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral or sterically hindered precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators requiring specific three-dimensional structures.
• Ligand and Catalyst Development: Acts as a backbone for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed as a monomer or functional additive in the development of advanced polymers with tailored thermal or mechanical properties.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes to study enzyme mechanisms or protein interactions.
• Fine Chemical Production: Functions as a high-value intermediate in custom synthesis and contract manufacturing for specialty chemicals.

Basic Information

Product Name	4-Methoxybicyclo[2.2.2]octane-1-carboxylic Acid
CAS No.	773-34-2
Molecular Formula	C10H16O3
Molecular Weight	184.23 g/mol
Synonyms	1-Carboxy-4-methoxybicyclo[2.2.2]octane; 4-Methoxy-2-bicyclo[2.2.2]octanecarboxylic Acid; Bicyclo[2.2.2]octane-1-carboxylic acid, 4-methoxy-; 4-Methoxybicyclo[2.2.2]octane-1-carboxylic acid; 4-Methoxy-2-norbornanecarboxylic acid (related structural name); 4-Methoxyquinuclidine-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Methoxybicyclo[2.2.2]octane-1-carboxylic acid is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications in GMP-oriented research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases, strong oxidizing agents, and strong reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.