Description

1-Dodecyne is a terminal alkyne with a linear twelve-carbon chain, serving as a versatile and valuable building block in advanced organic synthesis. Its structure makes it a crucial intermediate for constructing complex molecules, particularly in the development of specialty polymers, liquid crystals, and pharmaceutical agents. This high-purity chemical is essential for research and production in industries including pharmaceuticals, agrochemicals, and materials science, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring long alkyl chain modifications.
• Agrochemical Synthesis: Serves as a key precursor for manufacturing herbicides, fungicides, and plant growth regulators with tailored hydrophobic properties.
• Polymer & Material Science: Acts as a monomer or chain extender in the production of specialty polymers, polyacetylenes, and advanced materials with specific optical or mechanical properties.
• Liquid Crystal Production: Employed in the synthesis of liquid crystal compounds for display technologies due to its rod-like molecular structure.
• Organic Synthesis & Catalysis: Utilized in Sonogashira coupling and other cross-coupling reactions to introduce alkyne functionalities into complex organic frameworks.
• Surface Chemistry & Coatings: Used to create self-assembled monolayers (SAMs) and hydrophobic surface treatments.
• Flavor & Fragrance Industry: Acts as an intermediate for synthesizing specific aroma chemicals and musk analogs.
• Research & Development: A fundamental reagent in academic and industrial R&D labs for exploring new synthetic methodologies and material properties.

Basic Information

Product Name	1-Dodecyne
CAS No.	765-03-7
Molecular Formula	C₁₂H₂₂
Molecular Weight	166.30 g/mol
Synonyms	Dodec-1-yne; n-Decylethyne; n-Decylacetylene; 1-Decyne, 2-ethyl-; Laurylene; Terminal Dodecyne; Alkylacetylene C12; Linear C12 Alkyne
EINECS	212-124-2

Quality Control

Our 1-Dodecyne is manufactured under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including GC, IR, and NMR, to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable, and our quality systems are designed to support regulatory requirements for our customers in critical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from heat, sparks, and open flames. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong oxidizing agents and strong acids. Containers should be kept tightly sealed to prevent moisture absorption and evaporation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.1%
Density at 20°C	0.765 - 0.775 g/mL
Refractive Index (n20/D)	1.435 - 1.445

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.