Description

2-Chloroethanesulfonyl Fluoride is a versatile and highly reactive organosulfur building block, primarily valued for its role as a key sulfonylating agent in advanced chemical synthesis. Its unique structure, featuring both a reactive sulfonyl fluoride group and a chloroethyl moiety, makes it an essential intermediate for constructing complex molecules with specific functionalities. This compound is particularly critical for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of sulfonamide-based drugs and other bioactive molecules.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides that incorporate sulfonyl groups.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialty polymers with sulfone linkages.
• Chemical Biology & Proteomics: Employed in activity-based protein profiling (ABPP) and the development of covalent enzyme inhibitors due to the reactivity of the sulfonyl fluoride group.
• Material Science: Utilized in the surface modification of materials and the creation of functional coatings.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing the chloroethanesulfonyl moiety into target molecules.

Basic Information

Product Name	2-Chloroethanesulfonyl Fluoride
CAS No.	762-70-9
Molecular Formula	C2H4ClFO2S
Molecular Weight	146.56 g/mol
Synonyms	2-Chloroethanesulfonyl fluoride; 2-Chloroethylsulfonyl fluoride; 2-Chloroethane-1-sulfonyl fluoride; 1-Chloro-2-fluoro sulfonylethane; Ethanesulfonyl fluoride, 2-chloro-; CESF; Chloroethylsulfonyl fluoride; 2-Chloroethyl sulfone fluoride
EINECS	Contact for details

Quality Control

Our 2-Chloroethanesulfonyl Fluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its reactive nature, it is recommended to store under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.