Description

N,N'-Bis(4-Nitrophenyl)Carbodiimide is a specialized aromatic carbodiimide compound, widely recognized for its role as a versatile coupling agent and chemical intermediate. This high-purity material is critical for facilitating amide bond formation and other condensation reactions under mild conditions, offering significant advantages in synthetic efficiency. It is an essential reagent for research and development laboratories, pharmaceutical synthesis, and advanced material science applications where precise molecular assembly is required.

Application

• Peptide Synthesis: Acts as a key coupling agent for the formation of amide bonds in solid-phase and solution-phase peptide synthesis.
• Pharmaceutical Intermediates: Used in the synthesis of complex drug molecules, particularly those containing nitrophenyl or carbodiimide functional groups.
• Polymer Chemistry: Serves as a cross-linking agent or chain extender in the production of polyurethanes, polyureas, and other specialty polymers.
• Bioconjugation: Facilitates the covalent attachment of proteins, antibodies, or other biomolecules to surfaces, nanoparticles, or other molecules for diagnostic and therapeutic applications.
• Material Science: Employed in the surface modification and functionalization of materials to introduce specific chemical properties.
• Organic Synthesis Reagent: A valuable reagent for dehydration reactions, enabling the synthesis of nitriles, imines, and other functional groups from carboxylic acids and amines.

Basic Information

Product Name	N,N'-Bis(4-Nitrophenyl)Carbodiimide
CAS No.	738-66-9
Molecular Formula	C13H8N4O4
Molecular Weight	284.23 g/mol
Synonyms	1,1'-(Carbodiimido)bis(4-nitrobenzene); Bis(4-nitrophenyl)carbodiimide; 4,4'-Dinitrocarbanilide N,N'-Carbodiimide; DNC; p,p'-Dinitrocarbanilide Carbodiimide; 1,3-Bis(4-nitrophenyl)carbodiimide; 4-Nitrophenyl carbodiimide dimer; (4-Nitrophenyl)carbodiimide dimer
EINECS	Contact for details

Quality Control

Our N,N'-Bis(4-Nitrophenyl)Carbodiimide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and FT-IR to confirm identity and assay. A comprehensive Certificate of Analysis (COA) detailing purity, physical characteristics, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong acids, bases, and oxidizing agents. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.