Description

Trans,Trans,trans-Cyclobutanetetracarboxylic Acid is a high-purity, multifunctional organic acid building block characterized by its unique rigid cyclobutane core and four carboxylic acid groups. This compound is valued for its ability to impart structural rigidity and high functionality in advanced polymer synthesis and as a precursor for complex molecular architectures. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for applications requiring precise molecular geometry and polyfunctionality.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block or linker in the synthesis of complex active pharmaceutical ingredients (APIs) and prodrugs.
• Polymer Chemistry: Acts as a tetrafunctional monomer or cross-linking agent for producing high-performance polyamides, polyimides, and polyester resins with enhanced thermal and mechanical properties.
• Metal-Organic Frameworks (MOFs): Utilized as an organic linker or strut in the design and construction of novel MOFs for gas storage, separation, and catalysis.
• Agrochemical Synthesis: Employed as an intermediate in the development of advanced herbicides, fungicides, and plant growth regulators.
• Chelating Agent: Functions as a multidentate ligand for metal ion complexation in analytical chemistry and industrial water treatment processes.
• Academic & Industrial Research: A valuable reagent for exploring new reactions in organic synthesis and materials science due to its stereochemistry and multiple reactive sites.

Basic Information

Product Name	Trans,Trans,trans-Cyclobutanetetracarboxylic Acid
CAS No.	720-21-8
Molecular Formula	C8H8O8
Molecular Weight	232.15 g/mol
Synonyms	(1r,2r,3r,4r)-Cyclobutane-1,2,3,4-tetracarboxylic Acid; all-trans-Cyclobutanetetracarboxylic Acid; r,r,r,r-Cyclobutanetetracarboxylic Acid; Cyclobutane-1,2,3,4-tetracarboxylic Acid, (1R,2R,3R,4R)-; CBTA; TTTC; 1,2,3,4-Cyclobutanetetracarboxylic Acid
EINECS	Contact for details

Quality Control

Our Trans,Trans,trans-Cyclobutanetetracarboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets exacting standards for research and industrial use. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (all-trans isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.