Description

6-Nitro-1,3-benzodioxole-5-carboxylic acid is a specialized nitroaromatic carboxylic acid derivative featuring a 1,3-benzodioxole (methylenedioxyphenyl) core structure. This compound serves as a critical high-purity synthetic intermediate for the development of complex organic molecules, particularly in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in fine chemical synthesis, where its unique functional groups enable targeted chemical transformations.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting neurological or anti-infective pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides, leveraging the bioactivity of the benzodioxole and nitro groups.
• Organic Synthesis & Material Science: Serves as a precursor for ligands, catalysts, or functional monomers in advanced polymer and material applications.
• Dye & Pigment Intermediate: Employed in the production of specialized nitroaromatic dyes and colorants.
• Academic & Contract Research: Essential reagent for methodological studies and custom synthesis projects in university and CRO laboratories.

Basic Information

Product Name	6-Nitro-1,3-Benzodioxole-5-Carboxylic Acid
CAS No.	716-32-5
Molecular Formula	C8H5NO6
Molecular Weight	211.13 g/mol
Synonyms	5-Carboxy-6-nitro-1,3-benzodioxole; 6-Nitro-1,3-benzodioxole-5-carboxylic acid; 6-Nitro-piperonylic acid; Piperonylic acid, 6-nitro-; 5-Nitro-2,3-methylenedioxybenzoic acid; 2,3-(Methylenedioxy)-5-nitrobenzoic acid; 6-Nitro-1,3-benzodioxol-5-ylcarboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Nitro-1,3-benzodioxole-5-carboxylic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Yellow to off-yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.