Description

(Z)-α-Chlorocinnamic Acid CAS NO 705-55-5 is a high-purity, stereospecific organic intermediate characterized by its α-chloro and cinnamic acid functional groups. This compound is valued for its role as a versatile building block in the synthesis of more complex molecules, particularly in pharmaceutical and fine chemical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing chiral frameworks and introducing specific functional handles.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring a specific (Z)-stereochemistry.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & OLED Material Research: Serves as a building block for creating advanced organic electronic materials and liquid crystal monomers.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, including dyes, fragrances, and UV absorbers.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis, including cross-coupling reactions and cyclization processes.
• Peptidomimetic & Bioactive Molecule Development: Utilized to incorporate the cinnamoyl moiety into peptide analogs and other bioactive compounds.

Basic Information

Product Name	(Z)-α-Chlorocinnamic Acid
CAS No.	705-55-5
Molecular Formula	C9H7ClO2
Molecular Weight	182.60 g/mol
Synonyms	(Z)-2-Chloro-3-phenylpropenoic Acid; (Z)-α-Chlorocinnamic Acid; (Z)-2-Chlorocinnamic Acid; (Z)-3-Phenyl-2-chloroacrylic Acid; (cis)-α-Chlorocinnamic Acid; (Z)-2-Chloro-3-phenylacrylic Acid; trans-2-Chlorocinnamic Acid (Isomer); 2-Chloro-(Z)-cinnamic Acid
EINECS	211-879-9

Quality Control

Our (Z)-α-Chlorocinnamic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and standard identification tests. We provide Certificates of Analysis (COA) with each shipment, detailing all critical parameters to ensure the material meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isomeric Purity (Z-Isomer)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.