Description

2'-Hydroxy-6'-Methoxyacetophenone is a specialized aromatic ketone derivative, recognized for its role as a key synthetic intermediate and building block in advanced organic chemistry. Its molecular structure, featuring both hydroxy and methoxy substituents, makes it a versatile precursor for the synthesis of more complex molecules, including pharmaceuticals and fine chemicals. This compound is particularly valuable for research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with complex phenolic or acetophenone-based structures.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and plant growth regulators where its specific substitution pattern is required.
• Fine Chemical Production: Acts as a precursor in the manufacture of dyes, pigments, UV absorbers, and other performance chemicals.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D labs for constructing heterocyclic compounds and exploring new catalytic reactions.
• Flavor & Fragrance Industry: Potential use as an intermediate in the synthesis of certain aroma chemicals, given its acetophenone backbone.
• Material Science: Investigated as a monomer or cross-linking agent in the development of specialized polymers and resins.

Basic Information

Product Name	2'-Hydroxy-6'-Methoxyacetophenone
CAS No.	703-23-1
Molecular Formula	C9H10O3
Molecular Weight	166.17 g/mol
Synonyms	1-(2-Hydroxy-6-methoxyphenyl)ethanone; 2'-Hydroxy-6'-methoxyacetophenone; 2-Acetyl-3-methoxyphenol; 6-Methoxy-2-hydroxyacetophenone; o-Hydroxy-m-methoxyacetophenone; 2-Hydroxy-6-methoxyacetophenone; NSC 403697
EINECS	211-879-8

Quality Control

Our 2'-Hydroxy-6'-Methoxyacetophenone is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We offer various grades, including standard and high-purity, to meet diverse application needs. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by techniques such as HPLC, GC, and NMR. We adhere to cGMP principles where applicable, and our quality commitment ensures the material is suitable for demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized; for long-term storage or opened containers, maintaining an inert atmosphere (e.g., under nitrogen or argon) is recommended to preserve stability and purity. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0% (Standard Grade) ≥99.0% (High Purity Grade)
Melting Point	48 - 52 °C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.