Description

4-Methylbicyclo[2.2.2]octane-1-carboxylic acid is a specialized bicyclic carboxylic acid derivative characterized by its rigid, cage-like molecular structure. This unique architecture makes it a valuable building block and intermediate in advanced organic synthesis, particularly for creating complex molecules with specific steric and electronic properties. It is primarily utilized by research institutions and industrial R&D departments focused on pharmaceuticals, agrochemicals, and material science.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of novel active pharmaceutical ingredients (APIs), especially for compounds requiring rigid, three-dimensional scaffolds.
• Agrochemical Research: Used in the synthesis of advanced pesticide and herbicide candidates, where its structural properties can influence biological activity and stability.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science: Employed in the research of advanced polymers and specialty chemicals where the bicyclo[2.2.2]octane core can impart thermal stability and unique material properties.
• Academic & Industrial R&D: A crucial reagent for methodological studies in organic chemistry, including studies on strain, reactivity, and molecular recognition.

Basic Information

Product Name	4-Methylbicyclo[2.2.2]octane-1-carboxylic acid
CAS No.	702-67-0
Molecular Formula	C10H16O2
Molecular Weight	168.23 g/mol
Synonyms	1-Carboxy-4-methylbicyclo[2.2.2]octane; 4-Methylbicyclo[2.2.2]octane-1-carboxylic acid; 4-Methyl-2,2,1-bicyclooctane-1-carboxylic acid; 4-Methyl-2,2,1-bicyclooctanecarboxylic acid; 1-Methylbicyclo[2.2.2]octane-4-carboxylic acid (isomer); Bicyclo[2.2.2]octane-1-carboxylic acid, 4-methyl-; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 4-Methylbicyclo[2.2.2]octane-1-carboxylic acid is produced and handled under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (by HPLC), identity (IR), and impurity profiles are available for every shipment, providing full traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability. The compound is compatible with strong acid/organic solvent environments but should be handled with standard laboratory precautions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.