Description

4-Fluoro-n-Methylbenzamide is a versatile fluorinated aromatic amide building block of significant importance in advanced organic synthesis. Its core value lies in providing a functionalized scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorine and amide functionalities into their target structures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and stability.
• Liquid Crystal Material Precursor: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
• Polymer Modification: Employed to introduce fluorinated aromatic groups into polymer chains, altering material properties like chemical resistance and thermal stability.
• Organic Electronic Materials: Acts as a component in the synthesis of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry research in academic and industrial laboratories.

Basic Information

Product Name	4-Fluoro-n-Methylbenzamide
CAS No.	701-49-5
Molecular Formula	C8H8FNO
Molecular Weight	153.15 g/mol
Synonyms	4-Fluoro-N-methylbenzamide; N-Methyl-4-fluorobenzamide; p-Fluoro-N-methylbenzamide; 4-Fluoro-N-methyl-benzenecarboxamide; 701-49-5; Benzamide, 4-fluoro-N-methyl-; N-Methyl-p-fluorobenzamide
EINECS	Contact for details

Quality Control

Our 4-Fluoro-n-Methylbenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	102 - 106 °C
Loss on Drying	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.