Description

1,1,3-Trichlorotrifluoroacetone is a versatile halogenated ketone intermediate of significant importance in advanced chemical synthesis. This compound is valued for its unique reactivity profile, enabling the introduction of trifluoromethyl and chlorinated functional groups into target molecules. It is primarily sought by R&D chemists and process engineers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex molecules, particularly those requiring trifluoromethylated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the introduction of fluorine atoms improves efficacy and environmental profile.
• Fluorochemical Production: Serves as a precursor for various fluorinated compounds, including specialty solvents, surfactants, and polymers.
• Organic Synthesis Reagent: Employed in laboratories for nucleophilic substitution and condensation reactions to construct complex organic frameworks.
• Material Science Research: Investigated for use in creating novel fluorinated materials with specific thermal, chemical, or surface properties.

Basic Information

Product Name	1,1,3-Trichlorotrifluoroacetone
CAS No.	79-52-7
Molecular Formula	C3Cl3F3O
Molecular Weight	215.38 g/mol
Synonyms	Trifluoro-1,1,3-trichloroacetone; 1,1,3-Trichloro-1,3,3-trifluoroacetone; 3,3,3-Trifluoro-1,1,3-trichloroacetone; Acetone, 1,1,3-trichloro-1,3,3-trifluoro-; TCTFA; Perchlorofluoroacetone; 1,1,3-Trichlorotrifluoro-2-propanone
EINECS	201-210-6

Quality Control

Our 1,1,3-Trichlorotrifluoroacetone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and reducing agents. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.65 g/mL
Boiling Point	~120-122°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.