Description

Chlorodifluoroacetic Acid is a versatile fluorinated organic acid building block, valued for its strong acidity and the unique reactivity imparted by its chlorine and fluorine substituents. This compound is essential for introducing the difluoroacetate moiety into target molecules, enabling the synthesis of advanced materials and active pharmaceutical ingredients. It is a critical raw material for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel fluorinated compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a difluoroacetate functional group.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and plant growth regulators that benefit from fluorine's properties.
• Organic Synthesis Reagent: Serves as a strong acid catalyst and a precursor for various nucleophilic substitution and esterification reactions in fine chemical manufacturing.
• Material Science: Employed in the research and development of fluorinated polymers, surfactants, and liquid crystals with enhanced stability and performance.
• Biochemical Research: Utilized as a metabolic probe or inhibitor in biochemical studies due to its ability to mimic acetic acid while altering reactivity.

Basic Information

Product Name	Chlorodifluoroacetic Acid
CAS No.	76-04-0
Molecular Formula	C2HClF2O2
Molecular Weight	130.48 g/mol
Synonyms	2-Chloro-2,2-difluoroacetic Acid; Chlorodifluoroethanoic Acid; Difluorochloroacetic Acid; Monochlorodifluoroacetic Acid; CDFA; α,α-Difluoro-α-chloroacetic Acid
EINECS	200-925-7

Quality Control

Our Chlorodifluoroacetic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including assay by titration and identification by FT-IR, to ensure it meets precise chemical and physical specifications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area, away from incompatible materials such as strong bases and oxidizing agents. Due to its nature as a strong acid/organic solvent, it is recommended to handle and store in corrosion-resistant containers. For long-term stability, storage at controlled room temperature (15-25°C) is advised.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (Titration)	≥ 98.0 %
Water Content (KF)	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.