Description

6-(2-Chloroacetyl)-8-Fluoro-2H-Benzo[B][1,4]Oxazin-3(4H)-One is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key synthetic intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate its unique benzoxazinone scaffold into new molecular entities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides, leveraging the biological activity of the fluorinated benzoxazinone core.
• Organic Synthesis Building Block: Used in medicinal chemistry for lead optimization and structure-activity relationship (SAR) studies due to its reactive chloroacetyl and lactam functionalities.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Material Science Research: Potential intermediate for creating specialty polymers or advanced materials with specific electronic or photophysical properties.

Basic Information

Item	Details
Product Name	6-(2-Chloroacetyl)-8-Fluoro-2H-Benzo[B][1,4]Oxazin-3(4H)-One
CAS No.	698984-57-5
Molecular Formula	C10H7ClFNO3
Molecular Weight	243.62 g/mol
Synonyms	8-Fluoro-6-(2-chloroacetyl)-3,4-dihydro-2H-1,4-benzoxazin-3-one; 6-(Chloroacetyl)-8-fluoro-2H-1,4-benzoxazin-3(4H)-one; 8-Fluoro-6-(chloroacetyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-3-one; 698984-57-5; 6-(2-Chloroacetyl)-8-fluoro-3,4-dihydro-2H-benzo[b][1,4]oxazin-3-one; 8-Fluoro-6-(2-chloroacetyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
EINECS	Contact for details

Quality Control

Our 6-(2-Chloroacetyl)-8-Fluoro-2H-Benzo[B][1,4]Oxazin-3(4H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.