Description

2H-Pyran-4-Amine,3,4-Dihydro-N,N,2-Trimethyl-,(2R,4S)-(9Ci) is a chiral, substituted dihydropyran derivative with a defined stereochemistry, serving as a valuable synthetic intermediate in advanced organic chemistry. Its precise stereochemical configuration makes it a critical building block for the development of enantiomerically pure compounds, particularly in the pharmaceutical sector. This high-purity intermediate is essential for researchers and process chemists in pharmaceutical R&D, agrochemical synthesis, and fine chemical manufacturing who require reliable, structurally defined components for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used in the production of advanced, stereospecific pesticides and herbicides where biological activity is dependent on molecular configuration.
• Fine Chemical Manufacturing: Serves as a precursor for specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & Industrial Research: A valuable reagent in methodological chemistry research, including catalysis studies and the development of new asymmetric synthesis protocols.
• Material Science Precursor: Potential use in the synthesis of functionalized organic materials and ligands for metal-organic frameworks (MOFs).

Basic Information

Product Name	2H-Pyran-4-Amine,3,4-Dihydro-N,N,2-Trimethyl-,(2R,4S)-(9Ci)
CAS No.	697752-35-5
Molecular Formula	C8H17NO
Molecular Weight	143.23 g/mol
Synonyms	(2R,4S)-3,4-Dihydro-N,N,2-trimethyl-2H-pyran-4-amine; (2R,4S)-4-Amino-3,4-dihydro-2,2,N,N-tetramethyl-2H-pyran; 2H-Pyran-4-amine, 3,4-dihydro-N,N,2-trimethyl-, (2R,4S)-; (2R,4S)-N,N,2-Trimethyl-3,4-dihydro-2H-pyran-4-amine; 697752-35-5; (2R-cis)-3,4-Dihydro-N,N,2-trimethyl-2H-pyran-4-amine
EINECS	Contact for details

Quality Control

Our production of 2H-Pyran-4-Amine,3,4-Dihydro-N,N,2-Trimethyl-,(2R,4S)-(9Ci) adheres to stringent quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, GC-MS, and NMR spectroscopy. Certificates of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles are provided with every shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.