Description

2-Bromo-4-(Trimethylstannyl)-Pyridine is a high-value organotin intermediate featuring a reactive bromine atom and a trimethylstannyl group on a pyridine scaffold. This compound is essential for advanced organic synthesis, particularly in cross-coupling reactions like Stille couplings, enabling the efficient construction of complex heterocyclic systems. It is primarily utilized by pharmaceutical R&D and agrochemical laboratories for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially in creating complex pyridine-based molecules for oncology and CNS research.
• Stille Coupling Reagent: Serves as a versatile organotin donor in palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides that require specific pyridine derivatives.
• Material Science Research: Employed in the creation of organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules due to the reactivity of the bromine and tin functional groups.
• Catalyst Ligand Precursor: Can be modified to create novel ligands for transition metal catalysts used in fine chemical synthesis.

Basic Information

Item	Detail
Product Name	2-Bromo-4-(Trimethylstannyl)-Pyridine
CAS No.	697300-77-9
Molecular Formula	C8H12BrNSn
Molecular Weight	328.79 g/mol
Synonyms	4-Trimethylstannyl-2-bromopyridine; 2-Bromo-4-(trimethylstannyl)pyridine; 2-Bromo-4-trimethylstannylpyridine; Pyridine, 2-bromo-4-(trimethylstannyl)-; (2-Bromopyridin-4-yl)trimethylstannane; Trimethyl(2-bromopyridin-4-yl)stannane; Stannane, trimethyl(2-bromopyridin-4-yl)-
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-(Trimethylstannyl)-Pyridine is produced and tested under strict quality management protocols. We ensure high purity and consistency through advanced analytical techniques, including NMR (¹H, ¹³C), HPLC, and GC analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. Due to its moisture-sensitive and easily oxidized nature, the container should only be opened in a controlled, dry environment and resealed immediately after use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.