Description

3-Bromo-2-Fluoro-5-(Trimethylstannyl)-Pyridine is a high-value organotin intermediate featuring a halogenated pyridine core. This compound is critical for facilitating efficient cross-coupling reactions, enabling the synthesis of complex molecules with precision. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) via Stille cross-coupling reactions.
• Agrochemical Research: Used to create novel fungicides, herbicides, and insecticides by introducing the pyridine-tin moiety into target structures.
• Material Science: Serves as a precursor for functionalized polymers and organic electronic materials, such as OLEDs and semiconductors.
• Chemical Synthesis: Enables the efficient introduction of the 3-bromo-2-fluoro-5-pyridyl group into complex organic molecules under mild conditions.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and coordination chemistry.
• R&D Scale-up: Supports process development from laboratory to pilot plant scale for new chemical entities.

Basic Information

Product Name	3-Bromo-2-Fluoro-5-(Trimethylstannyl)-Pyridine
CAS No.	697300-74-6
Molecular Formula	C8H11BrFNSn
Molecular Weight	347.78 g/mol
Synonyms	5-(Trimethylstannyl)-3-bromo-2-fluoropyridine; 3-Bromo-2-fluoro-5-(trimethylstannyl)pyridine; 2-Fluoro-3-bromo-5-(trimethylstannyl)pyridine; Pyridine, 3-bromo-2-fluoro-5-(trimethylstannyl)-; (3-Bromo-2-fluoro-5-pyridinyl)trimethylstannane; Trimethyl(3-bromo-2-fluoro-5-pyridinyl)stannane; Stannane, (3-bromo-2-fluoro-5-pyridinyl)trimethyl-
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Fluoro-5-(Trimethylstannyl)-Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR (1H, 13C, 19F, 119Sn) for structural confirmation and HPLC/GC analysis for purity and impurity profiling. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and batch-to-batch consistency for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥95% (Typical 97-99%)
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.