Description

1,4-Dihydro-Chromeno[4,3-C]Pyrazole-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 694507-52-3. This compound is a critical building block in modern medicinal chemistry, valued for its fused heterocyclic structure which serves as a core scaffold for developing novel therapeutic agents. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the synthesis of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a privileged scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Employed in the research and development of new APIs, particularly those with chromene and pyrazole pharmacophores.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	1,4-Dihydro-Chromeno[4,3-C]Pyrazole-3-Carboxylic Acid
CAS No.	694507-52-3
Molecular Formula	C12H8N2O3
Molecular Weight	228.20 g/mol
Synonyms	Chromeno[4,3-c]pyrazole-3-carboxylic acid, 1,4-dihydro-; 1,4-Dihydrochromeno[4,3-c]pyrazole-3-carboxylic acid; 1H-Chromeno[4,3-c]pyrazole-3-carboxylic acid, 1,4-dihydro-; 694507-52-3; 1,4-Dihydro-1H-chromeno[4,3-c]pyrazole-3-carboxylic acid; 3-Carboxy-1,4-dihydrochromeno[4,3-c]pyrazole
EINECS	Contact for details

Quality Control

Our 1,4-Dihydro-Chromeno[4,3-C]Pyrazole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.