Description

(2-Amino-2-Iminoethyl)Carbamic Acid tert-Butyl Ester Monohydrochloride is a protected guanidine derivative primarily used as a key synthetic intermediate in organic and medicinal chemistry. Its value lies in providing a stable, reactive handle for the controlled introduction of the guanidine functional group, a crucial motif in many biologically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical industry, particularly for developing protease inhibitors, peptide mimetics, and other therapeutic agents targeting cardiovascular and metabolic diseases.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, especially those containing guanidine or amidine pharmacophores.
• Protease Inhibitor Development: Used in the research and production of inhibitors for enzymes like thrombin, trypsin, and factor Xa, which are targets for anticoagulant and antiviral therapies.
• Peptide & Peptidomimetic Synthesis: Serves as a protected arginine analogue for constructing modified peptides with enhanced stability, bioavailability, or receptor binding affinity.
• Chemical Biology Research: Employed as a tool compound for studying protein-protein interactions and enzyme mechanisms where guanidinium groups play a role.
• Agrochemical Synthesis: Potential intermediate in creating novel pesticides or herbicides that utilize guanidine-based chemistry for activity.
• Material Science Precursor: Can be used in the development of specialty polymers or functionalized surfaces that require specific nitrogen-rich moieties.

Basic Information

Product Name	(2-Amino-2-Iminoethyl)Carbamic Acid tert-Butyl Ester Monohydrochloride
CAS No.	691898-38-1
Molecular Formula	C7H16ClN3O2
Molecular Weight	209.67 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-N'-amidino-ethylenediamine Hydrochloride; Boc-Guanidine Hydrochloride; tert-Butyl N-(2-Amino-2-iminoethyl)carbamate Hydrochloride; 2-[(tert-Butoxycarbonyl)amino]-1-iminoethylamine Hydrochloride; NG-Boc-Guanidine HCl; 1-Amino-1-(tert-butoxycarbonylamino)methaniminium Chloride; (2-Amino-2-iminoethyl)-carbamic acid 1,1-dimethylethyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our (2-Amino-2-Iminoethyl)Carbamic Acid tert-Butyl Ester Monohydrochloride is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D and scale-up. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles. We support compliance with cGMP, ICH Q7, and other relevant regulatory guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.