Description

2H-Pyran-2-Carboxylicacid,6-Ethyltetrahydro-,(2R,6R)-Rel-(9Ci) is a high-purity, stereochemically defined chiral intermediate of significant interest in advanced organic synthesis. Its value lies in its precise molecular architecture, which serves as a critical building block for the development of complex, biologically active molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those working on novel active ingredients, chiral catalysts, and fine chemical synthesis where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new Active Pharmaceutical Ingredients (APIs), especially in medicinal chemistry programs targeting complex molecular scaffolds.
• Agrochemical Synthesis: Used in the development of advanced, stereoselective pesticides and herbicides where specific enantiomeric forms are required for optimal activity and environmental profile.
• Catalyst & Ligand Development: Serves as a precursor for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis to induce high enantioselectivity.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty and performance chemicals where the tetrahydro-2H-pyran carboxylic acid core structure is a desired motif.
• Academic & Industrial R&D: A valuable reference standard and starting material for methodological studies in synthetic organic chemistry, particularly in stereoselective ring formation and functionalization.

Basic Information

Product Name	2H-Pyran-2-Carboxylicacid,6-Ethyltetrahydro-,(2R,6R)-Rel-(9Ci)
CAS No.	690629-90-4
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	(2R,6R)-rel-6-Ethyltetrahydro-2H-pyran-2-carboxylic acid; 6-Ethyltetrahydro-2H-pyran-2-carboxylic acid, (2R,6R)-rel-; 690629-90-4; (rel-(2R,6R))-6-Ethyltetrahydro-2H-pyran-2-carboxylic acid; 2H-Pyran-2-carboxylic acid, 6-ethyltetrahydro-, (2R,6R)-rel-; Tetrahydro-6-ethyl-2H-pyran-2-carboxylic acid (relative (2R,6R) configuration)
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Identity and purity are confirmed through advanced analytical techniques including HPLC, chiral chromatography, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% e.e. (rel-(2R,6R))
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.