Description

Cyclobutanecarboxylic Acid, 1-Amino-2-Methyl-, (1R,2S)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures with precise three-dimensional control, which is critical for developing bioactive molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, process development, and the synthesis of novel active ingredients.

Application

• As a chiral synthon in the asymmetric synthesis of pharmaceutical candidates.
• Intermediate for the development of protease inhibitors and other enzyme-targeted therapeutics.
• Building block in the research and scale-up of agrochemicals, such as herbicides and fungicides with specific stereochemical requirements.
• Key starting material in process chemistry for the GMP production of active pharmaceutical ingredients (APIs).
• Utilized in academic and industrial R&D for exploring new chemical spaces and structure-activity relationships (SAR).
• Precursor for synthesizing custom ligands and catalysts used in stereoselective transformations.

Basic Information

Product Name	Cyclobutanecarboxylic Acid, 1-Amino-2-Methyl-, (1R,2S)- (9Ci)
CAS No.	689215-72-3
Molecular Formula	C6H11NO2
Molecular Weight	129.16 g/mol
Synonyms	(1R,2S)-1-Amino-2-methylcyclobutanecarboxylic acid; (1R,2S)-2-Methyl-1-aminocyclobutanecarboxylic acid; trans-1-Amino-2-methylcyclobutanecarboxylic acid (relative stereochemistry); 1-Amino-2-methylcyclobutanecarboxylic acid, (1R,2S)-; Cyclobutanecarboxylic acid, 1-amino-2-methyl-, (1R,2S)-; 689215-72-3; (1R,2S)-AMCBA
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with typical purities exceeding 97% (by HPLC), with enantiomeric excess (ee) specifications tailored to customer requirements. Certificates of Analysis (COA) are available upon request, detailing identity, purity, chiral purity, and residual solvent content. Our quality system supports development from research quantities through to cGMP manufacturing standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a dry environment to prevent degradation. For long-term storage, consider storing under nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.