Description

Cyclohexanecarboxaldehyde, 4-(Hydroxymethyl)-, cis- (9Ci) is a high-purity, functionalized cyclohexane derivative characterized by its aldehyde and hydroxymethyl groups in a cis-configuration. This compound serves as a versatile and valuable chiral building block for the synthesis of complex organic molecules, particularly in the pharmaceutical and fine chemical industries. It is primarily sought after by research chemists and process development scientists for applications in asymmetric synthesis, medicinal chemistry, and the production of advanced intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Asymmetric Synthesis: Utilized as a precursor for chiral ligands, catalysts, and auxiliaries in stereoselective chemical transformations.
• Fine Chemical Production: Serves as a building block for fragrances, agrochemicals, and specialty polymers requiring specific stereochemistry.
• Medicinal Chemistry & Drug Discovery: Used in research libraries and for constructing molecular scaffolds during the hit-to-lead and lead optimization phases.
• Academic & Industrial R&D: Employed in methodological studies and the development of new synthetic routes due to its defined stereochemistry and reactive functional groups.

Basic Information

Product Name	Cyclohexanecarboxaldehyde, 4-(Hydroxymethyl)-, cis- (9Ci)
CAS No.	688810-18-6
Molecular Formula	C8H14O2
Molecular Weight	142.20 g/mol
Synonyms	cis-4-(Hydroxymethyl)cyclohexanecarboxaldehyde; (1r,4r)-4-(Hydroxymethyl)cyclohexane-1-carbaldehyde; 4-(Hydroxymethyl)cyclohexanecarboxaldehyde (cis-); 4-Formylcyclohexylmethanol (cis-); cis-4-Formylcyclohexylmethanol; (cis)-4-(Hydroxymethyl)-1-cyclohexanecarboxaldehyde
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxaldehyde, 4-(Hydroxymethyl)-, cis- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, enantiomeric excess, and impurity profiles. Our quality management system supports compliance with cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee (cis-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.