Description

1-Cbz-4-(Piperidin-4-Yl)-Piperazine is a high-purity, protected piperazine-piperidine hybrid building block essential for advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate, enabling the construction of complex molecular architectures with potential biological activity. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for the synthesis of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry: Used for structure-activity relationship (SAR) studies and lead optimization due to its versatile piperazine-piperidine scaffold.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and optimization of API manufacturing processes.
• Chemical Biology: Employed in the development of chemical probes and tool compounds for biological target validation.
• Agrochemical Research: Utilized in the discovery and synthesis of new crop protection agents and pesticides.
• Custom Synthesis: A foundational component for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	1-Cbz-4-(Piperidin-4-Yl)-Piperazine
CAS No.	688020-80-6
Molecular Formula	C17H25N3O2
Molecular Weight	303.40 g/mol
Synonyms	1-[(Benzyloxy)carbonyl]-4-(4-piperidinyl)piperazine; 4-(Piperazin-1-yl)piperidine-1-carboxylic acid benzyl ester; 1-Cbz-4-(4-piperidyl)piperazine; N-Cbz-4-(4-piperidyl)piperazine; Benzyl 4-(piperidin-4-yl)piperazine-1-carboxylate; 4-(1-Piperazinyl)-1-piperidinecarboxylic Acid Phenylmethyl Ester; 688020-80-6
EINECS	Contact for details

Quality Control

Our 1-Cbz-4-(Piperidin-4-Yl)-Piperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to industry best practices, and specifications can be aligned with customer requirements for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.