Description

Chroman-8-Boronic Acid is a high-purity boronic acid derivative characterized by its chroman-based structure, serving as a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in creating novel pesticides and herbicides by constructing specific aromatic and heterocyclic frameworks.
• Material Science: Serves as a precursor for organic electronic materials, including OLEDs and organic semiconductors.
• Chemical Synthesis: Enables Suzuki-Miyaura cross-coupling reactions to form biaryl and other conjugated structures under mild conditions.
• Ligand & Catalyst Development: Utilized in the preparation of novel ligands for transition metal catalysis.
• Academic & R&D: A valuable reagent for methodological development and exploring new synthetic pathways in academic and industrial laboratories.

Basic Information

Product Name	Chroman-8-Boronic Acid
CAS No.	685514-79-8
Molecular Formula	C9H9BO3
Molecular Weight	176.0 g/mol
Synonyms	8-Boronochroman-8-ol; 8-Chromanylboronic Acid; Chroman-8-ylboronic Acid; 3,4-Dihydro-2H-1-benzopyran-8-boronic Acid; 8-(Hydroxyboranyl)chroman; 8-Borono-3,4-dihydro-2H-chromene; Chroman-8-boronic acid pinacol ester (precursor); 8-Boronochromane-8-ol
EINECS	Contact for details

Quality Control

Our Chroman-8-Boronic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity determination, NMR for structural confirmation, and Karl Fischer titration for moisture content. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.