Description

(3S,4S)-Methyl 4-Aminotetrahydro-2H-Pyran-3-Carboxylate Hydrobromide is a high-purity chiral building block and salt form of a key pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules where stereochemical control is paramount, ensuring the efficacy and safety of the final active pharmaceutical ingredient (API). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, particularly in areas requiring sophisticated organic synthesis.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the multi-step synthesis of complex drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Asymmetric Synthesis: Used as a building block in catalytic asymmetric reactions to construct stereochemically defined molecular architectures.
• Process Chemistry & Scale-Up: Employed in route development and optimization for the commercial manufacturing of APIs under Good Manufacturing Practice (GMP) standards.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and the discovery of new biological entities in drug discovery pipelines.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development, validation, and quality control in regulatory submissions.

Basic Information

Product Name	(3S,4S)-Methyl 4-Aminotetrahydro-2H-Pyran-3-Carboxylate Hydrobromide
CAS No.	683774-06-3
Molecular Formula	C7H14BrNO3
Molecular Weight	240.10 g/mol
Synonyms	Methyl (3S,4S)-4-aminooxane-3-carboxylate hydrobromide; (3S,4S)-4-Amino-tetrahydro-2H-pyran-3-carboxylic acid methyl ester hydrobromide; (3S,4S)-Methyl 4-aminotetrahydropyran-3-carboxylate HBr; 4-Aminotetrahydro-2H-pyran-3-carboxylic acid methyl ester (3S,4S)-hydrobromide; 683774-06-3; Methyl 4-aminotetrahydro-2H-pyran-3-carboxylate hydrobromide (stereoisomer)
EINECS	Contact for details

Quality Control

Our (3S,4S)-Methyl 4-Aminotetrahydro-2H-Pyran-3-Carboxylate Hydrobromide is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including chiral purity and residual solvent analysis, to support your regulatory and development needs. Certificates of Analysis (COA) detailing identity, purity, and specific tests are available for every batch and provided upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% de
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.