Description

3-Amino-3-(4-Hydroxy-3,5-Dimethyl-Phenyl)-Propionic Acid is a specialized aromatic amino acid derivative that serves as a high-value synthetic intermediate in advanced organic synthesis. Its unique structure, featuring both amino and phenolic hydroxyl functional groups, makes it a critical building block for constructing complex molecules with specific biological activity. This compound is primarily utilized by research institutions and pharmaceutical developers engaged in the creation of novel active pharmaceutical ingredients (APIs), peptide mimetics, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and metabolic disorder targets.
• Peptidomimetic Chemistry: Used to incorporate non-natural amino acid residues into peptide chains to enhance stability, bioavailability, and biological activity.
• Ligand Synthesis: Serves as a precursor for chelating agents and specialized ligands used in catalysis and metal complexation studies.
• Bioconjugation: The reactive amino and carboxylic acid groups enable its use in linker chemistry for antibody-drug conjugates (ADCs) and other bioconjugation applications.
• Academic & Industrial Research: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Acts as a starting material for the synthesis of dyes, advanced materials, and other specialty organic compounds.

Basic Information

Product Name	3-Amino-3-(4-Hydroxy-3,5-Dimethyl-Phenyl)-Propionic Acid
CAS No.	682803-99-2
Molecular Formula	C11H15NO3
Molecular Weight	209.24 g/mol
Synonyms	3-Amino-3-(4-hydroxy-3,5-dimethylphenyl)propanoic acid; β-Amino-β-(4-hydroxy-3,5-dimethylphenyl)propionic acid; 4-Hydroxy-3,5-dimethyl-β-phenyl-β-alanine; (3R/S)-3-Amino-3-(4-hydroxy-3,5-dimethylphenyl)propanoic acid; DL-3-Amino-3-(4-hydroxy-3,5-dimethylphenyl)propionic acid; 3-(4-Hydroxy-3,5-dimethylphenyl)-3-aminopropanoic acid; Amino acid derivative CAS 682803-99-2
EINECS	Contact for details

Quality Control

Our production of 3-Amino-3-(4-Hydroxy-3,5-Dimethyl-Phenyl)-Propionic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support development and cGMP-grade requirements, with specifications tailored to meet the rigorous standards of pharmaceutical and advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.