Description

3-Amino-3-(3-Ethoxy-4-Hydroxy-Phenyl)-Propionic Acid is a specialized aromatic amino acid derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its unique molecular scaffold, which combines a phenolic moiety with an amino acid backbone, enabling the development of novel compounds with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemical intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Peptidomimetic Research: Used to incorporate non-natural amino acid residues into peptide chains to enhance stability, bioavailability, and receptor binding affinity.
• Ligand Synthesis: Serves as a precursor for chelating agents and complex ligands in medicinal inorganic chemistry and diagnostic imaging.
• Bioconjugation Chemistry: The amino and carboxylic acid functional groups allow for site-specific conjugation in antibody-drug conjugate (ADC) and prodrug development.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme function and protein-protein interactions.
• Fine Chemical Synthesis: An important intermediate for creating complex, high-value specialty chemicals for agrochemical and material science applications.

Basic Information

Product Name	3-Amino-3-(3-Ethoxy-4-Hydroxy-Phenyl)-Propionic Acid
CAS No.	682803-60-7
Molecular Formula	C11H15NO4
Molecular Weight	225.24 g/mol
Synonyms	3-Amino-3-(3-ethoxy-4-hydroxyphenyl)propanoic acid; β-Amino-3-ethoxy-4-hydroxyhydrocinnamic acid; (3R/S)-Amino-3-(3-ethoxy-4-hydroxyphenyl)propionic acid; 3-(3-Ethoxy-4-hydroxyphenyl)-3-aminopropionic acid; DL-3-Amino-3-(3-ethoxy-4-hydroxy-phenyl)propionic acid; 3-Ethoxy-4-hydroxy-β-phenyl-β-alanine; Aromatic β-amino acid derivative
EINECS	Contact for details

Quality Control

Our 3-Amino-3-(3-Ethoxy-4-Hydroxy-Phenyl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with cGMP and ICH Q7 guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.