Description

3-Amino-3-(Pentamethyl-Phenyl)-Propionic Acid is a specialized aromatic amino acid derivative characterized by its unique pentamethylphenyl substituent. This structural motif makes it a valuable non-natural amino acid building block for advanced organic synthesis and pharmaceutical research. It is particularly sought after by R&D chemists and process development scientists in the fine chemical and life science sectors. The compound, with CAS number 682803-45-8, serves as a critical intermediate for constructing complex molecules with tailored properties.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in areas requiring constrained amino acid analogs.
• Peptidomimetics & Drug Design: Used to incorporate sterically hindered, hydrophobic amino acid residues into peptide backbones to enhance metabolic stability, bioavailability, and binding affinity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Employed in the synthesis of advanced crop protection agents and herbicides that require specific steric and electronic properties.
• Material Science: A potential monomer or functional additive for designing advanced polymers with specific thermal or mechanical characteristics.
• Chemical Biology Probes: Useful for labeling studies or as a building block for activity-based probes to study enzyme function.

Basic Information

Product Name	3-Amino-3-(Pentamethyl-Phenyl)-Propionic Acid
CAS No.	682803-45-8
Molecular Formula	C14H21NO2
Molecular Weight	235.32 g/mol
Synonyms	3-Amino-3-(2,3,4,5,6-pentamethylphenyl)propanoic acid; β-Amino-β-(pentamethylphenyl)propionic Acid; 3-Amino-3-(pentamethylphenyl)propanoic acid; (3-Amino-3-(2,3,4,5,6-pentamethylphenyl)propanoic acid); Pentamethylphenylalanine analog; 2,3,4,5,6-Pentamethyl-β-phenyl-β-alanine; 682803-45-8; NSC 828034
EINECS	Contact for details

Quality Control

Our 3-Amino-3-(Pentamethyl-Phenyl)-Propionic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets exacting R&D and process chemistry standards. Certificates of Analysis (COA) with full characterization data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.