Description

Cyclohexanecarboxylic Acid, 2,5-Dimethyl-, (1S,2R,5S)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its precise three-dimensional structure makes it a valuable intermediate for creating complex molecules with specific biological activity. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals. The CAS number for this material is 681448-22-6.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for creating stereocenters in complex drug molecules.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure pesticides and herbicides where specific stereochemistry is crucial for efficacy and environmental safety.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands and catalysts used in enantioselective chemical transformations.
• Fine Chemical & Flavor/Fragrance Ingredient: Employed in the synthesis of high-value specialty chemicals, including chiral components for advanced flavors and fragrances.
• Academic & Industrial Research: A critical reagent in methodological development and synthetic chemistry research within university and corporate R&D laboratories.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 2,5-Dimethyl-, (1S,2R,5S)- (9Ci)
CAS No.	681448-22-6
Molecular Formula	C9H16O2
Molecular Weight	156.22 g/mol
Synonyms	(1S,2R,5S)-2,5-Dimethylcyclohexanecarboxylic Acid; (-)-cis-2,5-Dimethylcyclohexanecarboxylic Acid; (1S,2R,5S)-2,5-Dimethyl-1-cyclohexanecarboxylic Acid; (1S,2R,5S)-rel-2,5-Dimethylcyclohexanecarboxylic Acid; Chiral 2,5-Dimethylcyclohexanecarboxylic Acid; CAS 681448-22-6
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxylic Acid, 2,5-Dimethyl-, (1S,2R,5S)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (ee) and chemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral assay are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.