Description

Cyclohexanepropanoic Acid, Alpha,α-Difluoro-β-Oxo- (9Ci) is a high-value fluorinated organic building block characterized by its reactive β-keto acid structure flanked by fluorine atoms. This compound matters for its role as a critical intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and advanced material science. It is needed by R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty polymers where the introduction of fluorine atoms is crucial for modulating biological activity, metabolic stability, and material properties.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of fluorinated drug candidates, including protease inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of advanced, fluorinated pesticides and herbicides with enhanced efficacy and environmental profile.
• Material Science: Acts as a monomer or cross-linking agent in the creation of specialty fluoropolymers with unique thermal and chemical resistance.
• Organic Synthesis Building Block: Employed in sophisticated organic reactions, such as Horner-Wadsworth-Emmons or Knoevenagel condensations, to construct complex fluorinated scaffolds.
• Chemical Research & Development: Essential for academic and industrial labs exploring new fluorination methodologies and the properties of fluorine-containing compounds.

Basic Information

Product Name	Cyclohexanepropanoic Acid, Alpha,α-Difluoro-β-Oxo- (9Ci)
CAS No.	681240-35-7
Molecular Formula	C9H12F2O3
Molecular Weight	206.19 g/mol
Synonyms	2,2-Difluoro-3-oxocyclohexanepropanoic Acid; 3-(2,2-Difluoro-3-oxocyclohexyl)propanoic Acid; α,α-Difluoro-β-oxocyclohexanepropanoic Acid; 681240-35-7; Cyclohexanepropanoic acid, α,α-difluoro-β-oxo- (9CI)
EINECS	Contact for details

Quality Control

Every batch of Cyclohexanepropanoic Acid, Alpha,α-Difluoro-β-Oxo- (9Ci) is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and process chemistry. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its sensitivity to strong alkali and fluoride-active conditions, keep away from incompatible materials. The container should be kept tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.