Description

2H-Pyran-2-Acetonitrile, Tetrahydro-4,6-Dihydroxy-, (2R,4R)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its value lies in its unique bicyclic structure with multiple functional handles, making it a versatile precursor for complex molecule construction. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in antiviral, anti-inflammatory, or neurological drug candidates.
• Agrochemical Synthesis: Used in the construction of complex, biologically active molecules for next-generation crop protection agents and herbicides.
• Asymmetric Catalysis Research: Serves as a valuable ligand precursor or a model substrate in the development of new stereoselective catalytic processes.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, fragrances, and advanced materials requiring high stereochemical purity.
• Academic & Institutional Research: A critical reagent for methodological studies in organic chemistry, total synthesis projects, and exploring new reaction pathways.

Basic Information

Product Name	2H-Pyran-2-Acetonitrile, Tetrahydro-4,6-Dihydroxy-, (2R,4R)- (9Ci)
CAS No.	676260-69-8
Molecular Formula	C7H11NO3
Molecular Weight	157.17 g/mol
Synonyms	(2R,4R)-Tetrahydro-4,6-dihydroxy-2H-pyran-2-acetonitrile; (2R,4R)-4,6-Dihydroxy-tetrahydro-2H-pyran-2-acetonitrile; 2H-Pyran-2-acetonitrile, tetrahydro-4,6-dihydroxy-, (2R,4R)-; (2R,4R)-THP Acetonitrile Diol Derivative; Chiral Dihydroxypyran Acetonitrile; 676260-69-8; (2R,4R)-Dihydroxy-tetrahydropyran-2-ylacetonitrile
EINECS	Contact for details

Quality Control

Our 2H-Pyran-2-Acetonitrile, Tetrahydro-4,6-Dihydroxy-, (2R,4R)- (9Ci) is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and stereochemical purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (2R,4R)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.