Description

6-Bromo-3,4-Dihydro-1H-Isochromen-4-Amine Hydrochloride is a high-purity, synthetically valuable organic building block and pharmaceutical intermediate. This compound matters for its role as a key precursor in the synthesis of complex molecules, particularly in medicinal chemistry research and development. It is primarily needed by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and fine chemical producers focused on developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for the discovery of new bioactive molecules.
• Organic Synthesis Reagent: Acts as a versatile synthon for constructing complex heterocyclic frameworks and isochromene derivatives in academic and industrial research.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.
• Agrochemical Research: Potential intermediate in the development of novel crop protection agents and pesticides.
• Material Science Precursor: Can be employed in the synthesis of specialized organic materials and ligands for catalysis.

Basic Information

Product Name	6-Bromo-3,4-Dihydro-1H-Isochromen-4-Amine Hydrochloride
CAS No.	676134-73-9
Molecular Formula	C9H9BrClNO
Molecular Weight	262.53 g/mol
Synonyms	6-Bromo-3,4-dihydro-1H-2-benzopyran-4-amine hydrochloride; 4-Amino-6-bromo-3,4-dihydro-1H-isochromene hydrochloride; 6-Bromo-1,2,3,4-tetrahydro-4-isoquinolinamine hydrochloride; 6-Bromo-3,4-dihydro-4-amino-1H-2-benzopyran hydrochloride; 6-Bromoisochroman-4-amine hydrochloride; 4-Amino-6-bromoisochroman hydrochloride; 676134-73-9
EINECS	Contact for details

Quality Control

Our 6-Bromo-3,4-Dihydro-1H-Isochromen-4-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.